Danielle Giliauskas

Comparing the effectiveness and adverse events of intranasal and intramuscular naloxone formulations for opioid overdose reversal

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Questions

  • What is the evidence of the effectiveness and adverse events of intranasal naloxone (NARCAN® Nasal Spray, 4 mg/0.1 mL) compared to intramuscular naloxone (0.4 mg/1 mL) for reversal of opioid overdose?

 Key take-home messages

  • Various intranasal and
doxycycline pills

Doxycycline prophylaxis for the prevention of bacterial sexually transmitted infections (STIs)

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Questions

  • What is the evidence to support the use of doxycycline for prevention of bacterial STIs (pre- and post-exposure prophylaxis)?

 Key take-home messages

  • Five studies from high-income settings have examined doxycycline as bacterial STI prophylaxis among men who
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