-People who use drugs – Page 2 – The Ontario HIV Treatment Network

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Possible benefits of providing safe supply of substances to people who use drugs during public health emergencies such as the COVID-19 pandemic

-Mental health or substance use, -Organization of care, -People who use drugs, News, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What are possible benefits of providing a safe supply of substances to people who use drugs during public health emergencies such as the COVID-19 pandemic? Key take-home messages Safe supply is an approach that focuses on saving lives by prescribing pharmaceutical grade substances such as opioids and stimulants to individuals at risk …

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Plane flying in clouds the colour of rainbows.

Sexualized drug use (chemsex and methamphetamine) and men who have sex with men

-Men who have sex with men, -Mental health or substance use, -Organization of care, -People who use drugs, News, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What is the impact of sexualized drug use (specifically of chemsex and methamphetamine) on the health of men who have sex with men? What are effective interventions and/or services that address chemsex and methamphetamine use among men who have sex with men (including prevention, harm reduction, engagement in care and treatment)? Key …

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Economic evaluations of pre- and post-exposure prophylaxis for HIV

-HIV prevention, -Men who have sex with men, -Organization of care, -People who use drugs, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What is the cost-effectiveness of HIV post-exposure prophylaxis? What is the cost-effectiveness of HIV pre-exposure prophylaxis? What are the gaps in literature? Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging (1). PrEP can be cost-effective or …

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Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV

-HIV prevention, -Men who have sex with men, -People who use drugs, -Women at risk, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What is the efficacy of oral tenofovir disoproxil fumarate with or without emtricitabine as pre-exposure prophylaxis (PrEP) for HIV in the context of clinical trials? Has this efficacy been realized in real-world implementation? What are the key factors implicated in its efficacy and what is the frequency of breakthrough infections? Key take-home …

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Interventions to reduce stigma among health care providers working with substance users

-Mental health or substance use, -Organization of care, -People who use drugs, -Social determinants of health, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What are effective interventions for reducing stigma among health care providers who work with substance users? Key take-home messages The attitudes and behaviours of practitioners have been linked to a variety of clinical outcomes in different patient groups (1, 2). The prevalence of stigma among health care providers towards people who use …

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NARCAN® Nasal Spray efficacy for emergency treatment of opioid overdose

-Mental health or substance use, -People who use drugs, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What is the difference in efficacy between NARCAN® Nasal Spray and naloxone administered by intramuscular injection? What are the considerations regarding ease of use of NARCAN® Nasal Spray? What is the possible impact of nasal passage blockage on efficacy of NARCAN® Nasal Spray? What is the role of fentanyl in chest wall …

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The effect of non-injection drug use on sexual risk behaviours and ART adherence among men who have sex with men

-Epidemiology and HIV care cascade, -Men who have sex with men, -Mental health or substance use, -People who use drugs, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What is the impact of non-injection drug use (i.e., the non-medical use of drugs) on ART adherence, sexual risk behaviours, and overall health among men who have sex with men? What are effective interventions to address the impact of non-injection drug use among men who have sex with men? Key take-home messages …

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Engaging law enforcement in harm reduction programs for people who inject drugs

-Mental health or substance use, -Organization of care, -People who use drugs, Rapid Responses / By Danielle Giliauskas

-+*Download pdf Questions What are the best ways of engaging law enforcement agencies in harm reduction programs for people who inject drugs? Key take-home messages Injection drug use is a major contributor to the spread of HIV and Hepatitis C in Canada (1–4). Laws and policing practices that govern injection drug use influence the risk …

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Chest compressions and rescue breathing when administering naloxone in opioid overdose

-Mental health or substance use, -Organization of care, -People who use drugs, Rapid Responses / By OHTN

-+*Download pdf Questions What does the evidence say about the use of chest compressions and/or the use of rescue breathing when responding to an opioid overdose and administering naloxone? Key take-home messages • Opioid overdoses cause respiratory failure (a reduction or stop in breathing), which can lead to cardiac arrest (1, 2). In the event …

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Hepatitis C reinfection after successful treatment

-Coinfections and comorbidities, -Men who have sex with men, -People who use drugs, News, Rapid Responses / By OHTN

-+*Despite these recent successes in HCV treatment, clinicians and health systems continue to be concerned about the risk of HCV recurrence — either due to reinfection following treatment or to late relapse after having had a sustained virological response.