-HIV prevention

E.g. PrEP, treatment as prevention

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The efficacy of post-exposure prophylaxis (PEP) for HIV

-+*Download pdf Questions What is the efficacy of PEP when used for non-occupational exposure? What is the efficacy of PEP when used for occupational exposure? Are specific PEP regimens more efficacious than others? What are key factors implicated in the efficacy or inefficacy of PEP?  Key take-home messages PEP initiated soon after exposure can reduce …

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Economic evaluations of pre- and post-exposure prophylaxis for HIV

-+*Download pdf Questions What is the cost-effectiveness of HIV post-exposure prophylaxis? What is the cost-effectiveness of HIV pre-exposure prophylaxis? What are the gaps in literature?  Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging (1). PrEP can be cost-effective or …

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Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV

-+*Download pdf Questions What is the efficacy of oral tenofovir disoproxil fumarate with or without emtricitabine as pre-exposure prophylaxis (PrEP) for HIV in the context of clinical trials? Has this efficacy been realized in real-world implementation? What are the key factors implicated in its efficacy and what is the frequency of breakthrough infections?  Key take-home …

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Rapid Response Service

Effective HIV prevention, education and outreach activities in African, Caribbean and Black communities

-+*Download pdf Questions What HIV prevention, education and outreach activities have been shown to be effective in African, Caribbean and Black communities?  Key take-home messages African, Caribbean and Black populations represent 14% of the HIV epidemic in Canada. To reduce new infections, HIV prevention intervention research is needed in these communities.(1) Programs that deliver education …

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Rapid Response Service

Gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)

-+*Download pdf Questions What are gay men’s attitudes to and perceptions of pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP)?  Key take-home messages There were fewer studies published on the potential use of non-occupational PEP (nPEP) among men who have sex with men than those on PrEP. Although 47% to 64% of men who have sex …

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Rapid Response Service

The willingness of PHAs living in high-income settings to negotiate condom use and use condoms during sex

-+*Download pdf Questions In high-income settings, what factors are associated with the willingness/ability of people living with HIV/AIDS (PHAs) to negotiate condom use, and to use condoms during sex?  Key take-home messages There is a controversial belief held by PHAs about the efficacy of HAART to reduce or prevent HIV transmission and/or an understanding of …

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