Rapid Responses – Page 6 – The Ontario HIV Treatment Network

The impact of location on implementation of HIV/STI prevention interventions among LGBTQ communities

-HIV prevention, -Men who have sex with men, -Organization of care, -Social determinants of health, News, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions What is the impact of geographical location on implementation of HIV/STI prevention programs or interventions among LGBTQ communities? Key take-home messages The characteristics of a location, including segregation, community-level stigma, and infrastructural resources, may influence HIV service utilization and the HIV continuum of care among men who have sex with men (1). […]

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Fire extinguisher sitting on the concrete floor

The efficacy of post-exposure prophylaxis (PEP) for HIV

-HIV prevention, -Men who have sex with men, -Organization of care, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions What is the efficacy of PEP when used for non-occupational exposure? What is the efficacy of PEP when used for occupational exposure? Are specific PEP regimens more efficacious than others? What are key factors implicated in the efficacy or inefficacy of PEP? Key take-home messages PEP initiated soon after exposure can reduce

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Bird's eye view of hands drawing a dollar sign in a sketchbook with a hot drink off to the side

Economic evaluations of pre- and post-exposure prophylaxis for HIV

-HIV prevention, -Men who have sex with men, -Organization of care, -People who use drugs, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions What is the cost-effectiveness of HIV post-exposure prophylaxis? What is the cost-effectiveness of HIV pre-exposure prophylaxis? What are the gaps in literature? Key take-home messages Economic evaluations of health care interventions can inform resource allocation and policy development. However, interpreting and generalizing results can be challenging (1). PrEP can be cost-effective or

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Methods to estimate the number of people living with undiagnosed HIV

-Epidemiology and HIV care cascade, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions How do we know how many people are living with undiagnosed HIV infection? What population groups make up people living with undiagnosed HIV infection? Key take-home messages At the end of 2016, the Public Health Agency of Canada estimated that 14% of 63,110 individuals living with HIV in Canada were undiagnosed (1).

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Postpartum women living with HIV: Challenges related to retention in care, treatment adherence, and mental health

-Epidemiology and HIV care cascade, -Mental health or substance use, -Organization of care, -Women at risk, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions What are the challenges related to retention in HIV care during the postpartum period? What are the challenges related to HIV treatment adherence during the postpartum period? What are the challenges related to postpartum depression among women living with HIV? What effective interventions or promising practices can be used to support women

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Looking up into a sky full of coloured umbrellas

Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV

-HIV prevention, -Men who have sex with men, -People who use drugs, -Women at risk, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions What is the efficacy of oral tenofovir disoproxil fumarate with or without emtricitabine as pre-exposure prophylaxis (PrEP) for HIV in the context of clinical trials? Has this efficacy been realized in real-world implementation? What are the key factors implicated in its efficacy and what is the frequency of breakthrough infections? Key take-home

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Group of people sitting on barrier overlooking water

Interventions to reduce stigma among health care providers working with substance users

-Mental health or substance use, -Organization of care, -People who use drugs, -Social determinants of health, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions What are effective interventions for reducing stigma among health care providers who work with substance users? Key take-home messages The attitudes and behaviours of practitioners have been linked to a variety of clinical outcomes in different patient groups (1, 2). The prevalence of stigma among health care providers towards people who use

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Considerations for the clinical management of HIV elite controllers

-Epidemiology and HIV care cascade, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions What is the prevalence of elite controllers among people living with HIV? What are the specific considerations regarding diagnostic testing of elite controllers? What is the recommended clinical management of elite controllers? Key take-home messages Fewer than one percent of people living with HIV are “elite controllers” (i.e. people who can spontaneously

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Nutrition and HIV

-Epidemiology and HIV care cascade, -Organization of care, Rapid Responses / Danielle Giliauskas

-+*Download pdf Questions Do people living with symptomatic HIV infection or AIDS require a therapeutic diet? Key take-home messages Nutrition is an important component of care for people living with HIV (1–5). Nutritional needs for people living with HIV can vary; therefore, dietary recommendations should be individualized to meet specific needs (1–3, 6). In general,

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