Rapid Responses

A doctor's notepad that says diagnosis syphillis with some coloured pills on the page

Interventions and best practices to address increasing rates of syphilis transmission

-Coinfections and comorbidities, -Organization of care, -Women at risk, News, Rapid Responses /

-+*Download pdf Questions What are the effective interventions and best practices to reduce syphilis transmission among various population groups?  Key take-home messages Infectious and congenital syphilis rates have seen a sharp growth in Canada since 2016 (1). The COVID-19 pandemic impact on syphilis rates is undetermined: some studies have shown that there are observed decreases […]

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Microscopic image of a virus

Low-level HIV viremia: Definitions, predictors, mechanisms, and clinical outcomes

-Epidemiology and HIV care cascade, -Organization of care, News, Rapid Responses /

-+*Download pdf Questions What are the factors associated with low-level HIV viremia? What are its possible mechanisms and clinical outcomes?  Key take-home messages The definitions of optimal viral suppression, low-level viremia, blips, virologic failure, and recommended management approaches to low-level viremia vary greatly across studies and clinical guidelines. There is controversy regarding the clinical implications

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Psychosocial needs and vulnerabilities of older gay and bisexual men

-Men who have sex with men, -Mental health or substance use, -Social determinants of health, News, Rapid Responses /

-+*Download pdf Questions What are the psychosocial needs and vulnerabilities of older gay and bisexual men? Key take-home messages Health outcomes related to the intersectionality of aging and sexual minority status is an emerging area of research (1, 2). It is important to consider the context of lived experiences among older gay men (3, 4),

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A requisition for an HIV test which resulted in negative and a bottle for 30 day of PrEP

Best practices of same-day HIV pre-exposure prophylaxis (PrEP) initiation

-HIV prevention, -HIV testing, -Organization of care, News, Rapid Responses /

-+*Download pdf Questions What are the best practices (including successes and challenges) of same-day HIV pre-exposure prophylaxis (PrEP) initiation after a negative HIV test result? Key take-home messages Several clinics have implemented same-day PrEP programs and have reported that clinics offering this model of care, in general, have positive health outcomes (1–5). Studies also report

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Immediate initiation of antiretroviral therapy (ART) after HIV diagnosis

-Epidemiology and HIV care cascade, -Organization of care, News, Rapid Responses /

-+*Download pdf Questions What are the best practices (including successes and challenges) of immediate initiation of ART after HIV testing and diagnosis? Key take-home messages The benefits of beginning antiretroviral therapy (ART) soon after HIV diagnosis include improved health outcomes across a wide variety of settings (1–5) as well as decreased long term  healthcare costs

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Close-up black-and-white photography of crystal methamphetamine

Factors associated with methamphetamine use among men who have sex with men

-Men who have sex with men, -Mental health or substance use, -People who use drugs, -Social determinants of health, News, Rapid Responses /

-+*Download pdf Questions What are the predictors of methamphetamine use among men who have sex with men?  Key take-home messages An abundance of literature details problematic sexualized drug use among men who have sex with men (1–3); additionally, several interventions attempt to address methamphetamine dependence in this population (4, 5). Several factors are associated with

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Incentive Program is written on a sticky note beside an eraser and two pencils

Effectiveness of and best practices for using contingency management and incentives for health care issues related to HIV, sexually transmitted infections (STIs), and pre-exposure prophylaxis (PrEP)

-Coinfections and comorbidities, -HIV prevention, -HIV testing, -Organization of care, News, Rapid Responses /

-+*Download pdf Question What is the effectiveness of and what are the best practices for using contingency management and incentives for health care issues such as HIV, STIs, and PrEP?  Key take-home messages Using contingency management and incentives at the different steps of HIV care continuum (such as testing, treatment adherence, viral suppressions) is widely

Effectiveness of and best practices for using contingency management and incentives for health care issues related to HIV, sexually transmitted infections (STIs), and pre-exposure prophylaxis (PrEP) Read More »

A syringe and pills beside a tag labelled 'Hepatitis C'

Effectiveness of and best practices for using contingency management and incentives in hepatitis C infection among people who use drugs

-Coinfections and comorbidities, -Organization of care, -People who use drugs, News, Rapid Responses /

-+*Download pdf Questions What is the effectiveness of and what are the best practices for using contingency management and incentives to support linkage to care and treatment for hepatitis C infection among people who use drugs?  Key take-home messages Recent studies in Canada have indicated that hepatitis C virus (HCV) treatment uptake among individuals who

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Impact of universal coverage for antiretroviral therapy (ART) on health outcomes

-Epidemiology and HIV care cascade, -Organization of care, News, Rapid Responses /

-+*Download pdf Question What are the benefits of universal antiretroviral therapy (ART) coverage on individual and population level health outcomes?  Key take-home messages As of 2017, the annual cost of single-tablet antiretrovirals (ART) in Ontario was estimated to be CAD 15,552 according to the Ontario Drug Benefit Formulary (1, 2). Universal, no-cost ART for all

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Pill bottles representing the seven classes of antiretroviral drugs

Impact of nonadherence to antiretroviral therapy (ART) on population-level health outcomes

-Epidemiology and HIV care cascade, -Organization of care, News, Rapid Responses /

-+*Download pdf Questions What is the impact of nonadherence to antiretroviral therapy (ART) on population-level health outcomes?  Key take-home messages Several studies analyze overall healthcare costs, pharmacy costs, and cost savings among people living with HIV relative to level of ART adherence (1–5). Generally, adherence to ART appears to predict levels of healthcare utilization, with

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