Rapid Responses

A syringe and pills beside a tag labelled 'Hepatitis C'

Effectiveness of and best practices for using contingency management and incentives in hepatitis C infection among people who use drugs

-+*Download pdf Questions What is the effectiveness of and what are the best practices for using contingency management and incentives to support linkage to care and treatment for hepatitis C infection among people who use drugs?  Key take-home messages Recent studies in Canada have indicated that hepatitis C virus (HCV) treatment uptake among individuals who …

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Impact of universal coverage for antiretroviral therapy (ART) on health outcomes

-+*Download pdf Question What are the benefits of universal antiretroviral therapy (ART) coverage on individual and population level health outcomes?  Key take-home messages As of 2017, the annual cost of single-tablet antiretrovirals (ART) in Ontario was estimated to be CAD 15,552 according to the Ontario Drug Benefit Formulary (1, 2). Universal, no-cost ART for all …

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Pill bottles representing the seven classes of antiretroviral drugs

Impact of nonadherence to antiretroviral therapy (ART) on population-level health outcomes

-+*Download pdf Questions What is the impact of nonadherence to antiretroviral therapy (ART) on population-level health outcomes?  Key take-home messages Several studies analyze overall healthcare costs, pharmacy costs, and cost savings among people living with HIV relative to level of ART adherence (1–5). Generally, adherence to ART appears to predict levels of healthcare utilization, with …

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Person using syringe on yellow substance

A review of structural, process, and outcome measures for supervised consumption services

-+*Download pdf Questions What structural, process, and outcome measures are used to monitor and evaluate the impact of supervised consumption services (SCS)?  Key take-home messages A 2019 systematic review identified several types of outcomes from scientific literature that guide assessment of SCS, including: usage by high-risk individuals, safe injection practice, overdose management, uptake of treatment …

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Laboratory (non-rapid) HIV testing in the emergency department: Methods, outcomes, and effectiveness

-+*Download pdf Questions What does the literature state regarding the methodology, outcome measures, and effectiveness of interventions that provide blood-based laboratory (non-rapid) HIV testing in emergency departments?  Key take-home messages There is a large body of evidence examining best practices, outcomes, impact, and other aspects of laboratory (non-rapid) HIV testing in emergency departments (EDs). Many …

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Best practices of using online and geosocial network applications to provide HIV and sexual health information to young newcomer men who have sex with men

-+*Download pdf Questions What are examples of online interventions providing HIV and sexual health information to young newcomer men who have sex with men originating from the top countries of citizenship among international students in Canada (such as China, India, Vietnam, South Korea, Mexico, Brazil and Nigeria)?  Key take-home messages There is a high HIV …

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Communicating the harms of methamphetamine use to men who have sex with men

-+*Download pdf Questions What are best practices for communicating the harms of methamphetamine use to men who have sex with men in order to prevent its uptake?  Key take-home messages Focus groups within the community can provide useful insight on how methamphetamine is used among men who have sex with men in the local context …

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Testing interventions for HIV and sexually transmitted infections (STIs) among young men who have sex with men

-+*Download pdf Questions What are effective interventions to increase uptake of HIV and sexually transmitted infections (STIs) testing among young men who have sex with men?  Key take-home messages In Canada in 2018, 63% of all HIV diagnoses among youth were attributed to gay, bisexual, and other men who have sex with men (1); similarly, …

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Effectiveness of take-home naloxone programs and availability of naloxone nasal spray in different jurisdictions

-+*Download pdf Questions What is the evidence of the effectiveness of take-home naloxone programs and administration of naloxone by laypeople? Which jurisdictions provide take-home naloxone programs? What is the current availability of naloxone nasal spray in different jurisdictions?  Key take-home messages There is wide support of take-home naloxone programs as they are associated with decreased …

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Interventions for immigrant Latino men who have sex with men along the HIV prevention and treatment cascade

-+*Download pdf Question What is the latest evidence regarding interventions for immigrant Latino men who have sex with men along the HIV prevention and treatment cascade?  Key take-home messages Among reported HIV cases with a known race/ethnicity in Canada in 2017, 6.3% were among individuals from Latin America (1). In 2018, Latinx persons in the …

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